Neutrophil Gelatinase-Associated Lipocalin Profile in Critically Ill Patients with Decreased of Consciousness
نویسندگان
چکیده
Background
 Neutrophil Gelatinase-Associated Lipocalin (NGAL) is an early marker of renal tubules damage. In critically ill patients,there are significant oxygenation disruptions to many organs particularly the kidneys and brain. Early recognition abnormalities in patients with a decreased consciousness may improve outcomes these patients.
 
 Objective
 To observe profile children level Hasan Sadikin Hospital Bandung.
 Method
 A cross-sectional study was performed on Hospital, Result
 Fifty-nine aged 2-15 years old were included study. There thirty-seven males (62.7%) twenty-two females (37.2%). this study, all had elevated urinary NGAL levels average value 606.95 ng/mL (1.20 -24629.59 ng/mL). We found that 30% developed sepsis caused by various etiologies which mostly malignancy 22 (37.3%) pneumonia 14 (23.7%). Of patients, 16.9% showed clinical improvement.
 Summary
 consciousness.
منابع مشابه
Evaluation of serum neutrophil gelatinase-associated lipocalin in predicting acute kidney injury in critically ill patients
Objective This investigation evaluated the real-time point-of-care testing (RT-POCT) of neutrophil gelatinase-associated lipocalin (NGAL) for detecting acute kidney injury (AKI) and prognosis of critically ill patients. Methods A total of 249 critically ill patients in the emergency department (ED), who were diagnosed with acute decompensated heart failure, sepsis or diabetic ketoacidosis were ...
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Urine neutrophil gelatinase-associated lipocalin (uNGAL) has shown promise as a biomarker for the early detection of acute kidney injury (AKI) in fixed models of injury, but its ability to predict AKI and provide prognostic information in critically ill adults is unknown. We prospectively studied a heterogeneous population of 451 critically ill adults, 64 (14%) and 86 (19%) of whom developed AK...
متن کاملPlasma and urine neutrophil gelatinase-associated lipocalin in the diagnosis of new onset acute kidney injury in critically ill patients
INTRODUCTION Neutrophil gelatinase-associated lipocalin (NGAL) has been demonstrated to be a useful early diagnostic biomarker of acute kidney injury (AKI) where the timing of the insult is certain. However, NGAL is not well validated in adult critical care practice because of indeterminate timing of injury. Therefore, we sought to establish the predictive ability of both urine and plasma NGAL ...
متن کاملUrinary neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in critically ill multiple trauma patients.
BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL), an iron-transporting protein rapidly accumulating in the kidney tubules and urine after nephrotoxic and ischemic insults, has been put forward as an early, sensitive, non-invasive biomarker for acute kidney injury (AKI). The aim of this study was to evaluate urinary NGAL levels as a predictor of early AKI (first 5 days after injury) ...
متن کاملContinuous renal replacement therapy in critically ill patients does not affect urinary neutrophil gelatinase-associated lipocalin levels
Failure 1 (5.5%) In the present study, we assessed urinary neutrophil gelatinase-associated lipocalin (uNGAL) during 24-hour continuous renal replacement therapy (CRRT) in critically ill patients. The study was performed in accordance with the Declaration of Helsinki and was approved by the Scientific Council and the Ethics Committee of Evangelismos Hospital in Athens, Greece. Informed consent ...
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2022
ISSN: ['1857-9655']
DOI: https://doi.org/10.3889/oamjms.2022.8020